Identification and characterization of cytosolic Hansenula polymorpha proteins belonging to the Hsp70 protein family
نویسندگان
چکیده
منابع مشابه
Characterization of the Hansenula polymorpha CPY gene encoding carboxypeptidase
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متن کاملCharacterization of the Hansenula polymorpha CPY gene encoding carboxypeptidase Y.
We have isolated the Hansenula polymorpha CPY gene encoding carboxypeptidase Y (Hp-CPY). The deduced amino acid sequence revealed that Hp-CPY consists of 541 amino acids and has a calculated Mr of 60,793. The protein is highly similar to Saccharomyces cerevisiae CPY (61.8% identity). At the N-terminus of Hp-CPY signals for the entry into the secretory pathway and subsequent sorting to the vacuo...
متن کاملPexophagy in Hansenula polymorpha.
In the yeast Hansenula polymorpha the development and turnover of peroxisomes is readily achieved by manipulation of the cultivation conditions. The organelles massively develop when the cells are incubated in the presence of methanol as the sole source of carbon and energy. However, they are rapidly and selectively degraded when methanol-grown cells are placed at conditions of repression of me...
متن کاملIdentification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family.
Clofibrate and many of its structural analogues induce proliferation of peroxisomes in the hepatic parenchymal cells of rodents and certain nonrodent species including primates. This induction is tissue specific, occurring mainly in the liver parenchymal cells and to a lesser extent in the kidney cortical epithelium. The induction of peroxisomes is associated with a predictable pleiotropic resp...
متن کاملMethanol oxidation and assimilation in Hansenula polymorpha
The metabolism of methanol was monitored in whole cells of the methylotrophic yeast Hansenula polymorpha by using [13C]methanol and n.m.r. in vivo. The main products observed under normal conditions were trehalose and glycerol, whereas cells that were starved before exposure to [13C]methanol also accumulated glutamate, glutamine and alanine; formate was also more prominent in spectra from starv...
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ژورنال
عنوان ژورنال: Yeast
سال: 1996
ISSN: 0749-503X
DOI: 10.1002/(sici)1097-0061(199607)12:9<849::aid-yea985>3.0.co;2-z